Current models of identifying prevalence of contact dermatitis from tea tree oil (TTO) rely on patch testing 5% oxidized TTO. This is in stark contrast with most other essential oils, which are tested as fresh oils at 2% concentrations. This testing and diagnostic approach produces an inaccurate diagnosis at the patient level and an inaccurate prevalence of contact dermatitis from TTO at the public health level.
This is caused by utilizing tests which measure contact dermatitis from oxidized TTO rather than dermatitis actually caused by fresh TTO.
This study will focus exclusively on patients with a self diagnosed reaction to TTO. This patient population will include patients who have legitimate reactions to TTO, fresh or oxidized, as well as those who do not.
To achieve 95% power with .05 signiﬁcance, assuming a 4:1 ratio of oxidized: true TTO reactions, a sample size of 42 is required.
Tea Tree Oil
Project Start Date
Wednesday, February 9, 2022
Project Completion Date
Thursday, September 15, 2022