In the present report, the focus moves from laboratory-based experiments to studies of inflammatory responses in an animal model. Tea tree oil was found to limit several types of inflammation, with the timing of its application being an important factor in obtaining a significant outcome. Typically, application was most effective if made close to the time of initiation of the inflammation, which would fit the likely clinical use. It is also important to note that tea tree oil did not lessen the swelling associated with sunburn.
In summary, this report provides further evidence that tea tree oil has potential as an anti-inflammatory agent. With the results of previous studies, it is an excellent foundation for further work in humans.