Utilisation of Australia’s rich floral resources has been a key impetus for development of new rural industries. Australia currently has a small, underdeveloped industry based on production and extraction of Centipeda cunninghamii, an endemic traditional medicinal plant. There is increasing national and international interest in high-quality C. cunninghamii extracts. This publication reports investigations on agronomic, harvest and postharvest issues which would assist in the development of a viable Australian Centipeda industry. This research aims to benefit current and potential farmers with experience in medicinal plant production and/or organic production as well as agricultural, medicinal plant, nutraceutical and cosmeceutical industry consultants.