Equine fetal post-mortem guidelines for veterinarians
Around 5% of Thoroughbred mares in Australia lose their pregnancies each year, resulting in significant welfare, environmental and economic impacts across the Thoroughbred industry. These...
THOROUGHBRED HORSES
Evaluating equine immune responses to new EHV-1 vaccine candidates
45 pages
Published: 1 Sep 2005
Author(s): Whalley, J M
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This report describes development towards potential new vaccines for EHV-1. Firstly the immunogenicity of a formulation containing EHV-1 envelope glycoproteins was tested by measuring antibody responses of mares and young foals. Secondly, in order to provide a system whereby these and other vaccines could be assessed, an experimental EHV-1 respiratory challenge model of infection was established in mares and foals, using an Australian isolate of EHV-1. This model was then used to determine whether the immune responses to the glycoprotein formulation could provide protection against EHV-1 infection.
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