Laminitis treatment by regional drug delivery to the horse’s foot

  • Published: 8 Oct 2014

  • Author(s): Pollitt, Christopher C.

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Laminitis is a crippling disease of horses’ feet in which the bone inside the foot detaches from its lamellar connections inside the hoof and descends downwards crushing the sensitive corium of the sole. No validated laminitis drug therapy exists, yet pharmaceutical agents with potential for laminitis prevention have been identified.

This project explored how anti-laminitis therapeutic agents could be delivered where they are most needed; directly to the horse’s foot. The novel research described in this report advances laminitis science by presenting a new investigative model for lamellar drug delivery and lamellar tissue analysis.