Characterisation and modulation of virulence of endemic IBDV strains using

CSIRO

  • Project code: PRJ-000698

  • Project stage: Closed

  • Project start date: Tuesday, July 1, 2003

  • Project completion date: Monday, April 30, 2007

  • National Priority: CME-Priority 4-Ensuring food safety of Australian chicken meat

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Program

Chicken Meat

Research Organisation

CSIRO

Objective Summary

To monitor genetic changes in circulating IBDV strains (Molecular Epidemiology) in order to determine if field strains are changing significantly To optimise the already developed Reverse Genetic system for IBDV for the genetic modification and the molecular characterisation of biological properties of IBDV To apply the Reverse Genetics system for the construction of recombinant IBDV to ascertain the importance of specific mutations in VP2 gene related to virulence and antigenicity and in particularhow these effect virulence of endemic strains