Improved control measures for infectious bursal disease virus (IBDV)
CSIRO
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Project code: PRJ-000699
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Project stage: Closed
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Project start date: Sunday, October 1, 2006
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Project completion date: Wednesday, September 29, 2010
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National Priority: CME-Priority 3-Contributing to efficient and secure chicken production systems
Summary
Improved disease management by identifcation of strains prevalent on commercial sites
Assurance to industry that strains circulating on commercial sites are not impacting on IBDV control or flock performance
Understanding of potential virulence determinants in circulating endemic starins of IBDV enabling advance warning of any impending increase of virulence.
Program
Chicken Meat
Research Organisation
CSIRO
Objective Summary
To continue monitoring genetic changes occurring in circulating IBDV field strains. To examine the pathogenicity of selected field isolates displaying unusual amino acids changes in SPF flocks. To apply the optimised reverse genetic system for IBDV to ascertain the importance of specific mutations within the VP2 gene related to virulence of endemic strains with a focus on understanding changes occurring in Australian strains.