Skin Sensitisation: Local Lymph Node Assay and Magnusson and Kliggmann Maxi

P Guinane Pty Ltd

  • Project code: PRJ-000819

  • Project stage: Closed

  • Project start date: Saturday, March 25, 2006

  • Project completion date: Sunday, January 28, 2007

  • National Priority: TTO-Increasing demand

Program

Tea Tree Oil

Research Organisation

P Guinane Pty Ltd

Objective Summary

1. To undertake a Local Lymph Node Assay in Mice (OECD429) to identify the contact allergenic potential of tea tree oil in order to provide a rational basis for risk assessment to the sensitising potential of tea tree oil to humans. 2. To test the allergenic potential of tea tree oil when administered to the skin of guinea pigs in order to provide a rational basis for risk assessment to the sensitising potential of tea tree oil to humans.