Genomic insights into multi-drug resistant Salmonella in Australian Thoroughbreds is a research project investigating the genetic makeup of Salmonella strains affecting Thoroughbred horses in Australia. Salmonella is a significant cause of illness and death in horses and poses risks to veterinarians, stud farms and, in some cases, human health due to antimicrobial resistance.
This project focuses on two Salmonella serotypes most commonly identified in Australian Thoroughbreds—Salmonella Muenster and Salmonella Typhimurium. Using whole genome sequencing, researchers are identifying key virulence factors and antimicrobial resistance genes to better understand why these strains cause disease, how they change over time, and the potential risks they pose to animal and public health.
By analysing stored Salmonella isolates collected from Thoroughbred horses over a five‑year period, the research is generating valuable molecular epidemiological data that will support improved disease surveillance, infection control and antimicrobial stewardship across the Thoroughbred industry. Findings will help veterinarians and stud farms make more informed decisions about Salmonella management, treatment options and biosecurity practices.
The outcomes of this project will contribute to improved horse health and welfare, reduced risk of disease transmission, and stronger evidence‑based approaches to managing antimicrobial resistance in equine settings. The research will also inform the development of industry‑relevant resources and future opportunities for disease prevention, including vaccine development.