In 2011 a significant increase in the number of Hendra virus infections of horses was observed. In response to this unprecedented number of Hendra virus spill-over events, the New South Wales, Queensland and federal government committed funds to research leading to strategies that minimise the impact of Hendra virus.
This report describes a project that was funded to develop serological assays to differentiate infected from vaccinated animals for Hendra virus. With the recent release of an equine vaccine for Hendra virus in Australia it was considered that it would be necessary to test horses on occasion to demonstrate that they were vaccinated and not infected with Hendra virus.