THOROUGHBRED HORSES 
34 pages
Published: 6 Jul 2026
Author(s): Noschka, E.
ISBN: 978-1-76053-630-5
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This report examines how oxidative stress markers can improve outcomes for equine colic, a major cause of death and economic loss in Australia’s $1.16 billion thoroughbred breeding industry.
About 4% of horses experience colic each year. Veterinarians often struggle to decide when surgery is needed. Delays can lead to severe intestinal damage or euthanasia, while early intervention can improve survival.
Current diagnostic tools do not work reliably across all cases, creating a need for better and more objective indicators.
The study focuses on isoprostanes in peritoneal fluid as an early marker of gut or uterine ischaemia. Researchers analysed 300 samples from veterinary hospitals in Australia and the United States using LC–mass spectrometry.
Results show that certain isoprostanes, such as 5‑F2t‑IsoP and Isofurane, rise with disease severity. Levels also differ between horses treated medically and those needing surgery.
Although the study could not set clear cut-off values, the findings support isoprostanes as useful biomarkers. They offer a promising way to guide surgery decisions.
This research supports development of a simple point-of-care test, which could improve animal welfare, assist veterinarians and strengthen industry outcomes.
Read the project snapshot here.
This report examines peritoneal fluid isoprostanes as biomarkers for equine colic severity and surgical need. Findings highlight their potential to improve early diagnosis and decision-making,...
This report examines peritoneal fluid isoprostanes as biomarkers for equine colic severity and surgical need. Findings highlight their potential to improve early diagnosis and decision-making,...
This project examines variability in laryngeal function in Thoroughbred yearlings during pre-sale endoscopy. It assesses how timing, location and technique affect grading consistency. Findings will...
This report examines strangles, a highly contagious horse disease caused by Streptococcus equi. Researchers tested 923 horses across 36 Australian properties and found 15% had...
This report examines strangles, a highly contagious horse disease caused by Streptococcus equi. Researchers tested 923 horses across 36 Australian properties and found 15% had...
Mare pregnancy loss in NSW and QLD Thoroughbreds: explore causes, risks and management to improve foal outcomes and productivity.
Australia’s thoroughbred breeding industry faces labour shortages, unclear career pathways and training gaps. This project overview outlines a practical workforce strategy to improve skills, retention...
Around 5% of Thoroughbred mares in Australia lose their pregnancies each year, resulting in significant welfare, environmental and economic impacts across the Thoroughbred industry. These...
This report explores a common genetic issue linked to early pregnancy loss in Australian Thoroughbred horses. It explains how better understanding this risk can help...
Genomic insights into multi-drug resistant Salmonella in Australian Thoroughbreds is a research project investigating the genetic makeup of Salmonella strains affecting Thoroughbred horses in Australia....
