THOROUGHBRED HORSES

Improved vaccine strategies for management of equine herpes viruses

  • 39 pages

  • Published: 1 Aug 2002

  • Author(s): Whalley, J. Millar, Love, Daria N.

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The report details the results of large scale serological surveys of the prevalence of antibody to EHV-1 and compares this 2000 data with that of 1995, obtained prior to vaccination. Secondly by using similar serological analysis and sampling mares and foals intensively over time, the percentage of mares and foals that respond to vaccination in the field was determined. Thirdly, new subunit vaccines based on virus protein or DNA were assessed for ability to induce antibody responses against EHV-1, and the results compared with those of the currently used whole virus vaccine. The development of new vaccines may offer extra protection against EHV-1 or EHV-4 disease and also provide the possibility of import replacement and export potential.